Maple Syrup Urine Disease (MSUD), also called branched-chain ketoaciduria, is an autosomal recessive metabolic disorder affecting branched-chain amino acids (BCAAs). Screening is conducted in the Philippines to detect MSU in newborns. This article discusses experimental research utilizing bacterial inhibition assay, specifically Escherichia coli MCC-MNH 1958, to detect excess BCAAs.
Describe bacterial inhibition assay and the procedure
Explain the uses of the bacterial inhibition assay
Discuss the potential of Escherichia coli to detect Maple Syrup Urine Disease
Jon Paul M. Reyes, PhD, RMT, AHI (AMT), MSMLS, MBA, CHRA, DPed