Description:
The variability in drug responses, concerns for drug dose safety, and prevention of adverse drug reactions gave rise to understanding an individual's genetic information to guide providers and pharmacists on the appropriate drug to prescribe and the appropriate dose. Mutations in the drug metabolism enzymes, cytochrome P450 (CYP450) could provide information on how a drug will be metabolized by an individual. This session will discuss the foundations of drug metabolism and the role of genetic variations and the different factors affecting metabolism of drugs. This session will also emphasize the role of laboratory scientists as an active member of the clinical care team to ensure patient safety.
Learning Objectives:
- Identify the drug metabolism pathway and drug delivery.
- Understand how genetic variations can impact drug metabolism.
- Discuss the role of molecular diagnostics in precision and personalized medicine.
Author(s):
Carlo Ledesma MS, MLS, DLM, QLS,
Launched: 2022