Description:
Altered expression or function of
adhesion molecules on leukemic blasts may contribute to the evolution and the biological behavior of acute leukemia. This article discusses the expression of
CD54 and CD62L by lymphoid cells and the serum level of shed L-selectin
(sL-selectin) in children with acute lymphoblastic leukemia (ALL) at initial
diagnosis and after the first remission, and the relationship to disease activity
and subtype.
Learning Objectives:
- Reflect on a study of 20 children diagnosed with ALL
- Discuss the relationship between disease activity and subtype
- Discuss the expression of CD54 and CD62L
Author(s):
F. M. Hafez
H. Hassab
Z. Morad
E. A. M. Farag
Launched: 2005